2. Harvard Epidemiologist Dr. Stephen Kissler discusses COVID-19 Mathematical Modeling & Variants

Harvard Epidemiologist, Dr. Stephen Kissler and John Houghton discuss data modeling for diseases with special consideration of SARS-CoV-2 variants, including B.1.1.7 (UK), P.1 (Brazil), and B.1.351 (South Africa).  This is a deep dive on the nuts and bolts of COVID-19 modeling including insightful definitions of R0, generation interval, start date, and population size. How R0… Continue reading 2. Harvard Epidemiologist Dr. Stephen Kissler discusses COVID-19 Mathematical Modeling & Variants

1. SARS-CoV-2 Attacks Germinal Centers, Implications for Herd Immunity and Reinfection

In our first episode, we discuss how SARS-CoV-2 attacks germinal centers in lymph nodes and spleens, resulting in a weakened immune response.  Review paper from the life sciences journal Cell:  Loss of Bcl-6-Expressing T Follicular Helper Cells and Germinal Centers in COVID-19.  Hosted by John Houghton, with special guests Dr. Faz Alam, Microbiologist and graduate… Continue reading 1. SARS-CoV-2 Attacks Germinal Centers, Implications for Herd Immunity and Reinfection